Endocrine Abstracts

Introduction: Mitochondrial diabetes (MD) is characterized by a broad spectrum of phenotypic and genotypic involvement. Through a cohort study of 40 patients with DM, we tried to correlate this diversity of phenotypic expression with the biomolecular substratum of the mitochondrial genome in the Tunisian population.Results: Epidemiologically and anthropometrically, our series fits the literature data with age at 31.6 years (5–52), female predominanc...

Diabetes is a factor favoring infections. Among which, the sepsis that becomes formidable and serious on this ground. The purpose of our work is to study the clinical, therapeutic and evolutionary features of sepsis in diabetics. A retrospective study of 43 cases of septicemia in diabetic patients collected at the service of Sfax Infectious Diseases. There were 22 men and 21 women, mean age 59 (20–78) years. Community origin was present in 88.4% of cases and nosocomial in...

Background: Azoospermia is present at approximately 1% of the man. karyotype can show number and structure abnormalities of the sexe chromosomes.Case: 16 years old boy,who was refered to the departement of endocrinology for a failure to growth since 8 years old. This patient was resulting from a marriage between blood relations. He had a congenital bilateral hip luxation diagnosed since birth but untreated.He had a gait disorder with a low weight 32 kg &...

Introduction: Deficiency of 17-βHSD3 is a rare autosomal recessive disorder of sex development manifesting in XY karyotype individuals. The presentation can range from partial or incomplete virilisation at birth to primary amenorrhoea and virilisation at puberty of an externally phenotypically female individual.Case reports: Case1 A 2-year-old girl presented with ambiguity of external genetalia. She had no significant past medical or surgical histor...

Introduction: Congenital hypothyroidism (CH) is the most common congenital endocrine disease since it affects 1/3000–1/4000 births. The involvement of genetics is no longer discussed and several genes have been implied in the different clinical forms of thyroid dysgenesis.Patients and methods: We report ten cases of thyroid dysgenesis collected at the pediatric and endocrinology departments of Sfax in Tunisia. The diagnosis was based on clinical, bi...

IntroductionDermatological manifestations associated with diabetes affect approximately 30% of patients. Diabetic Bullosis is a rare complication of diabetes. It is a rare bullous dermatosis charecterised by the occurrence of bubbles on healthy skin with variable levels of cleavage.ObjectiveWe propose to study the epidemiological, clinical and evolutionary characteristics of Diabetic Bullosis in diabetic pati...

IntroductionType 2 diabetes mellitus is a major non communicable disease which needs continuous and improved interventions. Knowledge assessment studies are useful for providing baselines for healthcare policies and educational programs.Aim of this studyTo evaluate diabetes-related knowledge among type 2 diabetes patients.MethodsA cross sectional study was conduct...

IntroductionPancreatitis is an inflammatory condition of the pancreas, which has known an increased incidence over the last years. Gallstones and alcohol abuse are the most common causes. But many risk factors are associated with pancreatitis, including Type 2 diabetes who has an estimated risk of pancreatitis at nearly three times the risk of non-diabetics. The aim of our work is to study the relationship between these two entities.<p class="abstext...

IntroductionThe association of type 1 diabetes with other autoimmune diseases is well known due to a common genetic terrain of varied clinical expressions. However, the occurrence of systemic diseases in diabetic patient, whatever the type of diabetes, is poorly studied. The objective of this study is to describe autoimmune and inflammatory diseases associated with diabetes.Materials and methodsIt ’ s a ...

Background: Diabetes mellitus poses a global chronic health challenge, with Tunisia experiencing a concerning surge in type 2 diabetes (T2D) prevalence. Cardiovascular and renal complications are prominent and severe consequences associated with T2D. Evaluating the costs related to managing these complications is crucial to enhance care quality, optimize resource utilization, and ultimately reduce the growing economic and social burden of this chronic disease.<p class="abs...